Effects of CYC27 on mean food intake, water intake and body weight during the seven week treatment. (A–C) show the food intake, water intake and body weight in BKS db mice during the seven week treatment with the vehicle, CYC27 and Rosiglitazone, and in BKS mice treated with vehicle. Data are shown as mean ± SD (n = 4). BKS—vehicle-treated normal BKS mice; BKS db—vehicle-treated diabetic BKS db mice; Rosiglitazone—Rosiglitazone, 50 mg·kg−1·day−1 Rosiglitazone-treated BKS db mice; CYC27-50, 50 mg·kg−1·day−1 CYC27-treated BKS db mice; CYC27-25—25 mg·kg−1·day−1 CYC27-treated BKS db mice.