Figure 3.

In combination, SAHA and EGCG significantly reduce the expression of miR-221/222 in two triple-negative breast cancer cell lines. (A) qRT-PCR was completed using MCF-7 cells after 3-day treatments with the indicated compounds using miR-221 and miR-222 primers (n = 3). RNU6B was used for comparison; (B–D) the same was done in MDA-MB-157, MDA-MB-231, and HCC1806 cells (n = 3). Error bars represent standard error of the mean (SEM); * p < 0.05, ** p < 0.01.