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Composition of mTOR-complexes. The functional domains of the mTOR protein are depicted in the center. The binding factors present in both TORC1 and TORC2 are shown in boxes (TTT, DEPTOR, mLST8). The TORC1-specific factors are shown in ovals on top of the figure (RAPTOR, PRAS40, FKBP12-rapamycin), while the TORC2-specific factors are shown at the bottom (RICTOR, PROTOR1/2, mSIN1).
