Skip to main content
. 2018 Dec 21;11(1):13. doi: 10.3390/cancers11010013

Figure 1.

Figure 1

Differential expression of ERα and human epidermal growth factor receptor 2 (HER2/ERBB2) in breast cancer cells and their response to tamoxifen (TAM). (A) Western blot analysis of ERα and HER2/ERBB2 expression in MCF7, SkBr3, BT-549, and MDA-MB-231. Both proteins were visualized on the same blot. (B) Quantification of band intensities of the indicated proteins after normalization to β-actin. (C) Immunofluorescence detection of ERα in MCF7 and BT-549 (at 100× magnification). (D) Immunofluorescence detection of HER2 in SkBr3 and BT-549 (at 100× magnification). Shown are the means ± SEM of at least three independent experiments. * p < 0.05 versus MCF7 cells and # p < 0.05 versus SkBr3 cells. TNBC: triple negative breast cancer.