Table 4.

List of metabolites associated with dominant rumen bacteria (>1%) affected by live yeast supplementation and their associated metabolic pathways.

Metabolites	Metabolic Pathway
Christensenellaceae R-7 group
Hypoxanthine	Purine metabolism
Hydroquinone	Riboflavin metabolism
Guanine	Purine metabolism
Glucose-1-phosphate	Glycolysis or gluconeogenesis, pentose and glucuronate interconversions, starch and sucrose metabolism, galactose metabolism, amino sugar and nucleotide sugar metabolism
Citrulline	Arginine and proline metabolism
Choline	Glycerophospholipid metabolism, glycine, serine and threonine metabolism,
5-hydroxyindole-3-acetic acid	Tryptophan metabolism
Uncultured bacterium (Bacteroidales BS11 gut group)
Glucose-1-phosphate	Glycolysis or gluconeogenesis, pentose and glucuronate interconversions, starch and sucrose metabolism, galactose metabolism, amino sugar and nucleotide sugar metabolism
Citrulline	Arginine and proline metabolism
Choline	glycerophospholipid metabolism, glycine, serine and threonine metabolism
Alanine-valine	Aminoacyl-tRNA biosynthesis, valine, leucine and isoleucine biosynthesis, selenoamino acid metabolism, alanine, aspartate and glutamate metabolism
Candidatus Saccharimonas
Spermidine	Beta-alanine metabolism, glutathione metabolism, arginine and proline metabolism