Table 1.
Patient Characteristics—Comparison between Early and Late Protein.
| Characteristic | Overall | Early Protein | Late Protein | p-Value |
|---|---|---|---|---|
| n | 2253 | 1040 | 1213 | |
| Age | 58.96 (18.32) | 59.22 (19.18) | 58.74 (17.55) | 0.537 |
| Male Sex | 1447 (64.2) | 651 (62.6) | 796 (65.6) | 0.147 |
| Weight | 80.22 (19.40) | 73.74 (13.91) | 85.78 (21.60) | <0.001 |
| Height | 1.70 (0.09) | 1.69 (0.09) | 1.70 (0.09) | <0.001 |
| Body surface area | 1.90 (0.22) | 1.84 (0.18) | 1.96 (0.23) | <0.001 |
| Body mass index | 27.91 (7.09) | 25.80 (4.47) | 29.72 (8.32) | <0.001 |
| SOFA score | 8.03 (3.57) | 7.69 (3.30) | 8.32 (3.77) | <0.001 |
| Ventilated | 2218 (98.4) | 1031 (99.1) | 1187 (97.9) | 0.023 |
| Vasopressors | 884 (39.2) | 396 (38.1) | 488 (40.2) | 0.317 |
| Cardiac | 365 (16.2) | 171 (16.4) | 194 (16.0) | 0.817 |
| Sepsis | 387 (17.2) | 169 (16.2) | 218 (18.0) | 0.306 |
| Surgical | 656 (29.1) | 311 (29.9) | 345 (28.4) | 0.475 |
| Trauma | 252 (11.2) | 131 (12.6) | 121 (10.0) | 0.057 |
| Respiratory | 379 (16.8) | 177 (17.0) | 202 (16.7) | 0.861 |
| Enteral Calories | 1334.64 (650.13) | 1457.64 (545.94) | 1227.77 (711.85) | <0.001 |
| Parenteral Calories | 346.28 (581.76) | 317.51 (578.83) | 371.29 (583.39) | 0.034 |
| Total Calories | 1684.17 (646.56) | 1780.17 (444.29) | 1601.87 (769.97) | <0.001 |
| Calculated energy expenditure | 2005.55 (485.01) | 1843.56 (347.63) | 2144.44 (540.05) | <0.001 |
| Administered calories to energy expenditure | 0.88 (0.37) | 0.98 (0.25) | 0.78 (0.42) | <0.001 |
| Significant parenteral nutrition | 311 (13.8) | 127 (12.2) | 184 (15.2) | 0.049 |
| Total protein delivered | 1058.74 (929.18) | 1193.92 (939.76) | 942.85 (904.45) | <0.001 |
| Daily protein delivered | 63.59 (19.00) | 71.18 (16.79) | 57.08 (18.35) | <0.001 |
| Daily protein, g/kg | 0.83 (0.28) | 0.98 (0.22) | 0.69 (0.26) | <0.001 |
| Daily protein, g/kg, first 3 days | 0.64 (0.33) | 0.93 (0.19) | 0.39 (0.19) | <0.001 |
| Daily protein, g/kg, other days | 0.87 (0.30) | 1.01 (0.24) | 0.75 (0.30) | <0.001 |
For continuous variables data presented as mean (sd) and discrete variables as n (%). SOFA: Sequential Organ Failure Assessment.