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. 2019 Jan 21;17(1):71. doi: 10.3390/md17010071

Table 2.

Novel conotoxin precursors identified in the four venom duct sections of C. tulipa by LC-MS/MS at 99% confidence.

1 Section Matched Precursor (S2) MS/MS Fragment PTM Precursor (Da) z
D Tu0051/T1.2 SNPACAGNNPH Ala->Gly@5 1169.430 2
D Tu316 AIASSVVTPGSSMK 1333.691 2
D Tu068 MINAETQTR 1062.510 2
D Tu065 NCMLINVQQLGLR Asn -> Thr @1, carbamidometh@2 1544.830 2
D Tu020 MLENLREAEVK Carboxy(E)@3 1374.681 3
DC Tu076 ADRDTDPDDENPR Oxidation(P)@7 1530.618 3
DC Tu056/T1.3 VKDFK 635.364 2
DC Tu316 AIASSVVTPGSSMK 1333.691 2
DC Tu065 NCMLINVQQLGLR 1524.820 2
DC Tu068 MINAETQTR 1062.500 2
DC Tu314 DLADTRYR Arg -> Ser @ 6 939.4289 2
DC Tu320 AAFHMFYFDQFSK 1637.730 3
PC Tu298/T6.4 DGTGQCAPK Gln->Asp@5, Carbamydomethyl @ 8, oxid(P)@10, 1190.560 3
PC Tu297/T6.4 VRDNR 658.351 2
PC Tu032/T6.1 DALKNLK 800.457 2
PC Tu035/TVIA SCNPYSR Carbamydometh@2, Deamidated(N)@3, Oxidation(P)@4, 899.342 2
PC Tu274/TVIA ALKNLKDSRGGSAR Deamidated(R)@8. 1474.787 2
PC Tu314 VVTSGSSLQGTSLK 1362.730 2
PC Tu075 VFIYGGCDGNANR 1428.640 2
PC Tu316 AIASSVVTPGSSMK 1333.690 2
PC Tu059/conopressin-T NLDNIEGH 910.413 2
PC Tu296/T6.4 VRDNR 658.340 2
PC Tu314 GIASKVVTSGSSLQ 1332.830 2
PC Tu030 VPEDASNLQGFDQG 1475.780 2
P Tu030 LPFNNVEGATNDLG QFEPSAENEDGKFRFF 1475.650 2
P Tu076 LTLSAPK Deam @ 3 728.443 2
P Tu075 AAFHMFYFDQFSK 1637.735 3
P Tu059/conopressin-T NLDNIEGH 910.414 2
P Tu314 FALKNPVLQINSGVTTSTPTGIEPGK Deamidated(N)@5; Deamidated(N)@11; Ser->Gly@12 2640.405 3
P Tu314 AVRAIASSVVTPGSSMKGGPLK 2112.360 3
P Tu314 VVTSGSSLQGTSLKDLADTRYRVTCAIQVENWTK 2321.149 3

1 Distal (D), Distal Central (DC), Proximal Central (PC) and Proximal (P).