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. 2018 Dec 20;11(1):7. doi: 10.3390/nu11010007

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Postmortem neurochemical assessments in the F2 and F3 offspring. Levels of the excitatory amino acids glutamate (A,B) and aspartate (C,D), as well as the inhibitory amino acids including glycine (E,F), GABA (G,H), and taurine (I,J) were measured by postmortem HPLC in the F2 and F3 offspring. Amino acids were measured in the mPFC, d.Hippo, and v.Hippo and expressed as ng/mg tissue weight. N (F2 CTR) = (8 M, 8 F), N (F2 HFD) = (8 M, 9F), N (F3 CTR) = (8 M, 9F), N (F3 HFD) = (8 M, 8F). All values are means ± SEM. * p < 0.05; ** p < 0.001; *** p < 0.0001. mPFC = medial prefrontal cortex, d.Hippo = dorsal hippocampus, v.Hippo = ventral hippocampus, HFD = high fat diet, CTR = control, F = female, M = male.