Table 1.

Summary of the observed cognitive phenotypes in F2 and F3 offspring.

Assessments	F1		F2		F3
	Male	Female	Male	Female	Male	Female
General locomotor activity	ø	ø	ø	ø	ø	ø
Working memory	ø	ø	ø	ø	ø	↓ at 24 h delay
Prepulse inhibition	↑	↑	↓↓	↑↑	↓↓	↑↑
Active avoidance learning	↓	↓	↓	↓	ø	ø
MK-801 sensitivity	↑	↑	↑↑↑	↓	↑↑↑	↓↓

The table summarizes the observed behavioral phenotypes of F1, F2, and F3 offspring born to HFD and chow-fed dams. ø = no change; ↑ = increased relative to control, ↓ = decreased relative to control.