Table 2.
Metabolites significantly changed in Parkinson’s disease differentiate between patients with or without zonisamide treatment.
| Compound, Relative Area | Ratio of Zonisamide (+) to Zonisamide (−) | p-Value |
|---|---|---|
| 1-methylnicotinamide | 1.61 | 0.0294 |
| AC(12:0) | 1.73 | 0.0407 |
| AC(12:1)-1 | 1.92 | 0.0405 |
| AC(16:1) | 1.75 | 0.0366 |
| AC(16:2) | 1.95 | 0.0054 |
| Glycerol | 0.843 | 0.0329 |
| Imidazolelactic acid | 1.50 | 0.0040 |
| Nervonic acid | 1.21 | 0.0068 |
| Oleoyl ethanolamine | 0.785 | 0.00146 |
| Ornithine | 1.32 | 0.0263 |
| S-methylcysteine | 0.726 | 0.0294 |
| Succinic acid | 1.46 | 0.0199 |
AC: acylcarnitine. p-Value obtained by Wilcoxon test.