Table 2.
Single nucleotide polymorphisms (SNPs) associated with gastric cancer with the smallest p-value for allele model.
| rsID | Gene | Minor Allele | OR (95% CI) (1) | p-Value (1) | FDR q-Value (1) | OR (95% CI) (2) | p-Value (2) | FDR q-Value (3) | OR (95% CI) (3) | p-Value (3) | FDR q-Value (3) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs3729931 | RAF1 | T | 1.54 (1.20–1.98) | 7.95 × 10−4 | 0.018 | 1.52 (1.18–1.96) | 1.29 × 10−3 | 0.028 | 1.52 (1.13–2.0) | 4.95 × 10−3 | 0.067 |
| rs45604736 | HRAS | C | 1.60 (1.16–2.22) | 4.68 × 10−3 | 0.036 | 1.58 (1.14–2.20) | 5.24 × 10−3 | 0.036 | 1.45 (1.01–2.11) | 4.89 × 10−2 | 0.189 |
| rs2283792 | MAPK1 | T | 1.45 (1.12–1.87) | 4.91 × 10−3 | 0.036 | 1.46 (1.13–1.90) | 5.23 × 10−3 | 0.036 | 1.48 (1.10–2.00) | 9.44 × 10−3 | 0.085 |
| rs9610417 | MAPK1 | T | 0.60 (0.42–0.87) | 6.64 × 10−3 | 0.037 | 0.59 (0.41–0.86) | 6.55 × 10−3 | 0.036 | 0.54 (0.35–0.82) | 3.89 × 10−3 | 0.067 |
(1) unadjusted, (2) adjusted by principal component (PC)1 and PC2 (242 cases and 242 controls), (3) adjusted by age, sex, PC1 and PC2 (242 cases and 242 controls). Minor allele is the effect allele. OR: Odds ratio; FDR: false discovery rate.