Table 5.
Summary of piglets orally administered scFvs and challenged with virulent PEDV.
| Treatment | Mortality Rate (%) a | Diarrhea Rate (%) a | Onset of Diarrhea (dpc) | Onset of Fecal RNA Shedding (dpc) | Peak Fecal RNA Shedding Titers (log10 copies/mL) a |
|---|---|---|---|---|---|
| Group1: scFv + PEDV (n = 4) | 0 (0/4) A | 25 (1/4) A | 3 | 2 | 4.87 ± 0.85 B |
| Group2: PBS + PEDV (n = 4) | 100 (4/4) B | 100 (4/4) B | 1 | 1 | 11.27 ± 1.42 A |
| Group3: PBS + PBS (n = 4) | 0 (0/4) A | 0 (0/4) A | ND | ND | ND |
a Different uppercase letters indicate a statistically significant difference between groups (p < 0.01). ND: Not detected.