Figure 3.

Hierarchical clustering dendrogram of different blueberry extracts (Elliot, Draper, Bluecrop, and Aurora), the extract of the blueberry–apple juice (BBAJ) from the human dietary intervention, and of four single compounds (quercetin, vitamin C, peondin, and cyanidin) based on the effect on the expression of 18 genes selected from a previously conducted human dietary interventions study. In order to compare these gene expression profiles with the profile generated in the human dietary intervention study, the gene expression profile of the human dietary intervention study is included as well (HDIS). Hierarchical clustering analysis was carried out using http://heatmapper.ca. As clustering method complete linkage was used, and distance between the clusters was computed based on Spearman rank correlation. The different conditions are displayed on the y-axis and the genes are shown on the x-axis.