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The Akt inhibitors could abolish the oncogenic role of ACP5 in CRC cells. A, B. Proliferation of HT-29 and SW480 cells treated with pcDNA3.1-ACP5 and (or) 1 μmol/L MK2206 by CCK-8 assay. C. Invasion of HT-29 and SW480 cells treated with pcDNA3.1-ACP5 and (or) 1 μmol/L MK2206 by transwell assay. Results shown are the mean ± SD (*P < 0.05, **P < 0.01, ***P < 0.001) of triplicate determination from three independent experiments.
