Figure 8.

ShRNA-ACP5 inhibits tumor growth by FAK/PI3K/AKT signaling in vivo. (A-C) Tumor xenograft volume (A), tumor size (B) and weight (C) in shRNA-ACP5-treated nude mice were smaller than that in the mock group. (D) ACP5 mRNA expression was decreased in shRNA-ACP5-treated nude mice, compared with control group. (E) Expression of phospho-FAK, phospho-PI3K, phospho-AKT proteins were decreased in shRNA-ACP5-treated nude mice, compared with control group. Results shown are the mean ± SD (**P < 0.01, ***P < 0.001).