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. 2019 Jan 1;9(1):64–78.

Figure 3.

Figure 3

CD7-CAR-NK-92MI and dCD7-CAR-NK-92MI cells specifically eliminated CD7-expressing T-ALL cell lines and primary tumor cells in vitro. A. At a 1:1 E:T cell ratio, CD7-CARNK-92MI and dCD7-CAR-NK-92MI cells targeted and lysed the CD7+ T-ALL cell line CCRF-CEM. B. CD7-CAR-NK-92MI and dCD7-CAR-NK-92MI cells showed specific lysis of CD7+ Jurkat cells at an E:T cell ratio of 1:1 or 5:1, the 7-AAD negative cell population represents the percentage of leftover Jurkat cells. C. At a 1:1 or 5:1 E:T cell ratio, the CD7-CAR-NK-92MI and dCD7-CAR-NK-92MI cells eliminated primary T-ALL tumor cells.