Table 1.
Overview of study population.
| Male [n] | Female [n] |
Disease Localization[n] |
Biopsy Localization [n] |
Medication [n] |
||
|---|---|---|---|---|---|---|
|
qPCR TaqMan arrays [n = 18] |
HN
ctrl.Colitis |
2
2 |
1
1 |
n.a. PC [2], PrC [1] |
S [2], cd [1] S [3] |
n.a. P [1], M [1] |
| CD_ni | 0 | 3 | PC [2], IC [1] | S [3] | P [2], Su [1], A [2], MD [1], CB [1] | |
| CD_i | 2 | 1 | PC [1], PrC [2] | S [3] | P [2], M [2], A [2], T [1] | |
| UC_ni | 1 | 2 | C [2], PrC [1] | S [3] | M [2], A [1] | |
| UC_i | 0 | 3 | PC [1], PrC [2] | S [3] | P [3], M [1], A [1], MD [2] | |
|
qPCR C1qB [n = 38] |
HN
Ctrl. colitis CD_ni |
2
2 2 |
3
5 5 |
n.a. C [7] IC [4], C [2], PC [1] |
ct [2], cd [2], S [1] ce [1], ct [2], S [3], R [1] ca [2], ct [1], S [4] |
CB [1] M [2], Su [1], MD [2], CB [2] P [3], B [1], M [4], Su [1], A [3], CP [1], MD [2], CB [1] |
| CD_i | 1 | 4 | IC [2], C [2], PC [1] | ce [1], ca [2], cd [1], S [1] | P [1], B [1], M [2], Su [1], A [3], Am [1], MD [2] | |
| UC_ni | 3 | 1 | C [2], PrC [2] | S [4] | P [1], M [2], A [3] | |
| UC_i | 5 | 5 | C [3], PC [6], PrC [1] | cd [2], S [7], R [1] | P [2], M [7], Su [1], A [4], MP [1] | |
|
SDS- PAGE [n = 25] |
HN
CD_ni CD_i |
2
3 2 |
4
12 2 |
n.a. I [2], IC [8], C [5] I [2], IC [2], PC [1] |
ti [6], fe [5] ti [6], fe [9] fe [4] |
n.a. P [3], B [1], M [7], Su [1], A [4], T [11], MD [1] B [1], M [1], T [1] |
|
IHC [n = 25] |
HN
CD_ni CD_i UC_ni UC_i |
n.a.
4 2 3 1 |
n.a.
6 1 4 3 |
n.a. I [1], IC [2], C [5], PC [2] C [1], PrC [1], PC [1] C [3], PrC [3], PC [1] C [1], PrC [1], PC [2] |
S [1] ca [3], ct [2], S [4], R [1] ca [1], S [2] ti [1], ce [1], ca [1], cd [2], S [2] cd [2], S [2] |
n.a. P [2], B [1], M [3], Su [2], A [3], MD [1], CB [1] P [1], M [2], Su [1], A [1] P [3], M [6], Su [1], A [4] P [2], M [3], Su [1], TL [1], MD [1], CB [1] |
|
Complement ELISA [n = 13] |
HN
CD_ni |
3
5 |
3
2 |
n.a. I [3], IC [3], C [1] |
NHS [6] NHS [7] |
n.a. P [1], B [1], M [4], A [2], T [7] |
HN = hospitalized normals, ctrl. Colitis = control colitis, CD = Crohn’s disease patients, UC = ulcerative colitis patients, i = patients with inflammation and active disease, ni = patients with no inflammation and in remission, n = number of patients, n.a. = not applicable, ti = terminal ileum, ce = cecum, S = sigma, cd = colon descendens, ca = colon ascendens, Ct = colon transversum, R = rectum, fe = feces, PC = pancolitis, PrC = proctocolitis, I = ileitis, IC = ileocolitis, C = colitis, P = Prednisone, B = Budesonide, M = Mesalamine, Su = Sulfasalazine, A = Azathioprine, CP = Cyclophosphamide, TL = Tacrolimus, MD = Metronidazole, CB = Ciprobay, T = anti-TNFα antibody, Am = Amox, MP = 6-Mercaptopurine, and NHS = normal human serum.