Table 3.
SPF and BEPFs values for tested formulations : P-334 (+SH) at 5.6%, M-Ser (OH) at 5.1%, P-334 +(SH) at 4.1% plus M-Ser (OH) at 2.9% and the reference containing BMDM at 4.5% and OMC at 2.6% (w/w). The values are expressed as mean ± SD (n = 4). Different letters indicate significant differences (p < 0.05) between different purified MAAs extracts for a UV-mediated effect (BEPF).
| UV-mediated Effects | P-334 (+SH) | M-Ser (OH) | MAA Combination | Reference |
|---|---|---|---|---|
| Erythema (SPF) | 4.53 ± 1.58 a | 6.47 ± 1 ab | 8.37 ± 2.12 bc | 9.54 ± 1.53 c |
| DNA Damage | 4.17 ± 1.55 a | 9.27 ± 1.98 b | 10.18 ± 2.99 b | 9.71 ± 1.58 b |
| Photocarcinogenesis (NMSC) | 4.60 ± 1.63 a | 7.55 ± 1.31 b | 8.74 ± 2.24 b | 9.50 ± 1.49 b |
| Systemic Immunosuppression (CHS) | 5.63 ± 2.23 a | 9.73 ± 2.17 b | 10.72 ± 2.99 b | 10.41 ± 1.68 b |
| Urocanic acid photoisomerization | 7.22 ± 3.21 a | 9.21 ± 2.37 a | 10.90 ± 2.95 a | 11.00 ± 2.38 a |
| Formation of singlet oxygen radicals | 6.51 ± 2.25 b | 2.62 ± 0.18 a | 6.45 ± 1.69 b | 9.74 ± 1.89 c |
| Photoaging | 4.81 ± 1.72 b | 2.16 ± 0.10 a | 4.37 ± 0.94 b | 10.63 ± 2.63 c |