Table 4.
Gene expression in liver on PND105.
| Gestation Diet | NP | HP | P | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Postweaning Diet | NP (n = 8) |
DSS1 (n = 8) |
DSS2 (n = 8) |
NP (n = 7) |
DSS1 (n = 8) |
DSS2 (n = 8) |
Gestation | Postweaning | Gestation × Postweaning |
| Gck | 1.00 ± 0.20 | 0.79 ± 0.19 | 0.60 ± 0.10 | 0.91 ± 0.29 | 0.62 ± 0.19 | 0.30 ± 0.06 | 0.20 | 0.02 * | 0.86 |
| Pklr | 1.00 ± 0.13 | 0.90 ± 0.10 | 0.75 ± 0.04 | 0.88 ± 0.09 | 0.71 ± 0.10 | 0.73 ± 0.06 | 0.20 | 0.06 | 0.62 |
| Fas | 1.00 ± 0.24 | 0.95 ± 0.14 | 0.58 ± 0.07 | 1.01 ± 0.17 | 0.77 ± 0.15 | 0.64 ± 0.09 | 0.76 | 0.03 * | 0.69 |
| Acc | 1.00 ± 0.22 | 0.91 ± 0.17 | 0.65 ± 0.10 | 0.73 ± 0.10 | 0.69 ± 0.10 | 0.61 ± 0.08 | 0.16 | 0.17 | 0.66 |
| Scd1 | 1.00 ± 0.25 | 0.88 ± 0.10 | 0.40 ± 0.12 | 0.62 ± 0.13 | 0.75 ± 0.22 | 0.43 ± 0.15 | 0.45 | 0.002 * | 0.62 |
| Screbf1c | 1.00 ± 0.13 | 1.14 ± 0.21 | 0.710 ± 0.18 | 0.96 ± 0.14 | 0.78 ± 0.10 | 0.61 ± 0.09 | 0.29 | 0.009 * | 0.52 |
| Pepck | 1.00 ± 0.12 a | 1.74 ± 0.44 a | 2.26 ± 0.19 a,b | 1.70 ± 0.80 a | 2.29 ± 0.66 a,b | 4.58 ± 0.77 b | 0.09 | <0.0001 * | 0.09 |
Data are means ± SEMs. Effects of diets were tested within model W (*, p < 0.05). Means that are significantly different (p < 0.05) according to the post-hoc test have different letters (a or b). GCK, Glucokinase; PKLR, Pyruvate kinase L/R; FAS, Fatty acid synthase; ACC, Acetyl-CoA carboxylase; SCD1, Stearoyl-CoA desaturase 1; SREBF1C, Sterol regulatory element-binding transcription factor 1 isoform c; PEPCK, Phosphoenolpyruvate carboxykinase; PND, Post-natal Day; NP, Normal-Protein (control); HP, High-Protein; DSS1, Dietary Self-Selection 1 (P and G/L in 2 different cups); DSS2, Dietary Self-Selection 2 (P, G and L in 3 different cups).