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. 2019 Jan 8;11(1):51. doi: 10.3390/cancers11010051

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Protein C (PC) activation mediated by thrombin, thrombomodulin (TM) and EPCR (endothelial protein C receptor) and its diverse biological functions (anticoagulant and cellular effects).