Table 2.
Concentration of circulating lipoprotein cholesterol and apolipoprotein profiles. Cholesterol content in very low density lipoprotein (VLDL), low density lipoprotein (LDL) and high density lipoprotein (HDL). Plasma level of apolipoprotein (Apo) A–I, B100, E, C–II and C–III. *** p < 0.001 vs. Ctrl and $ p < 0.05, $$ p < 0.01, $$$ p < 0.001 vs. WD (n = 9–10/group).
| Ctrl | WD | WDS1 | WDS2 | |
|---|---|---|---|---|
| Lipoproteins | ||||
| VLDL-C (mg/dL) | 3.9 ± 0.5 | 5.9 ± 0.3 | 3.3 ± 0.7 $ | 1.8 ± 0.4 $$$ |
| LDL-C (mg/dL) | 11.8 ± 0.3 | 57.2 ± 1.8 *** | 47.0 ± 5.2 | 30.2 ± 5.1 $$$ |
| HDL1-C (mg/dL) | 5.0 ± 0.3 | 50.1 ± 1.3 *** | 41.5 ± 5.2 | 27.4 ± 5.2 $$$ |
| HDL2-C (mg/dL) | 60.5 ± 3.1 | 160.8 ± 5.7 *** | 138.5 ± 6.8 | 106.3 ± 25.2 $$$ |
| Apolipoproteins | ||||
| Apo A-I (mg/dL) | 87.8 ± 8.6 | 946.7 ± 133.1 *** | 915.8 ± 192.3 | 419.1 ± 103.3 $ |
| Apo B100 (mg/dL) | 8.7 ± 1.0 | 19.9 ± 2.2 *** | 17.9 ± 1.4 | 13.3 ± 2.4 $ |
| Apo E (mg/dL) | 9.8 ± 0.4 | 60.0 ± 4.5 *** | 53.3 ± 7.3 | 29.2 ± 6.6 $$ |
| Apo C-II (mg/dL) | 0.7 ± 0.04 | 4.8 ± 0.3 *** | 3.8 ± 0.3 $ | 3.0 ± 0.3 $$$ |
| Apo C-III (mg/dL) | 8.9 ± 1.0 | 23.0 ± 3.1 *** | 15.6 ± 2.6 | 13.1 ± 2.1 $ |