Table 3.
Correlation between gallbladder UDCA content and biological variables in mice.
| Gallbladder UDCA (% Total BA) | ||
|---|---|---|
| Variables | r | p Value |
| Body weight | −0.69 | <0.0001 |
| Fasting glycemia | −0.38 | 0.02 |
| Fasting insulinemia | −0.49 | 0.003 |
| AUC GTT | −0.45 | 0.006 |
| ScAT weight | −0.65 | <0.0001 |
| Plasma total cholesterol | −0.72 | <0.0001 |
| Liver weight/Body weight ratio | −0.69 | <0.0001 |
| Fibrosis | −0.67 | <0.0001 |
| Steatosis | −0.64 | <0.0001 |
| Plasma ASAT | −0.59 | 0.0003 |
| Plasma ALAT | −0.68 | <0.0001 |
| Liver O2− | −0.56 | 0.02 |
| Liver NO | −0.60 | 0.005 |
| Liver Scd1 mRNA | −0.63 | <0.0001 |
| Liver Tgfβ1 mRNA | −0.64 | <0.0001 |
| Liver Col1a1 mRNA | −0.70 | <0.0001 |
| Liver Timp1 mRNA | −0.65 | <0.0001 |
AUC: Area under the curve; GTT: Glucose tolerance test; Scat: Subcutaneous adipose tissue; ASAT: Aspartate aminotransferase; ALAT: Alanine aminotransferase; O2−: superoxide anion; NO: nitric oxide; Scd-1: Stearoyl-CoA desaturase-1; Col1a1: Collagen type 1 α1; Timp1: Tissue inhibitor of metalloproteinase 1.