Skip to main content
. 2019 Jan 18;17(1):63. doi: 10.3390/md17010063

Figure 5.

Figure 5

Tetracenomycin X induces the proteasomal degradation of cyclin D1. (A) RT-PCR analysis of the gene expression of cyclin D1 in the A549 cells and H460 cells. (B) The A549 cells and H460 cells were pre-treated with MG132 at the indicated concentration for 2 h and then co-treated with tetracenomycin X (5 µmol/L) for 12 h. The A549 cells and H460 cells were pre-treated with DMSO or tetracenomycin X (5 µmol/L) and then co-treated with 10 μg/mL of cycloheximide (CHX) for the indicated times.