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Anti-proliferative activity of compounds 1k and 1n against different human cell lines (IC50).
| Compound | IC50 (µM) a | |||
|---|---|---|---|---|
| MCF-7 | HCT-116 | HeLa | CaCo2 | |
| 1k | 0.65 ± 0.05 | 1.93 ± 0.06 | 10.56 ± 0.98 | 1.06 ± 0.09 |
| 1n | 2.41 ± 0.23 | 3.55 ± 0.1 | 13.96 ± 1.41 | 3.33 ± 0.25 |
a IC50 value was calculated by plotting the percentage viability versus concentration on a logarithmic graph. Results are the mean values SD (standard deviation) of three separated experiment carried out in triplicate.
