Table 2.

Types of carrier solutions (adapted from Kusamura et al. (2008) [26]).

Type of Carrier Solution	Advantages	Disadvantages
Isotonic salt solutions and Dextrose solutions	Rapidly absorbed due to low molecular weight	Inability to maintain a prolonged high intraperitoneal fluid volume
Hypotonic solutions	Increases the cisplatin accumulation and enhances its cytotoxicity in vitro	Unexplained postoperative peritoneal bleeding
Hypertonic solutions	Allows prolonged high intraperitoneal volume Slows down the clearance of intraperitoneal fluid	Dilution of intraperitoneal drug due to fluid shift inward to the peritoneal cavity
Isotonic molecular weight solutions	Prolonged high intraperitoneal volume Reduced drug clearance from the peritoneal cavity	Drug exposure to the cancer cells is not significantly increased