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. 2019 Jan 7;11(1):108. doi: 10.3390/nu11010108

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Summary of synergistic mechanisms of SD bioactives in the vascular subnetwork: (a) component–target protein (round) or metabolite (triangle)–pathway network (); (b) complete sequence of six major metabolic pathways. The numbers in the box indicate the level of measured metabolites for the placebo (left) and SD (right) consumption group. SD, Sanghuang–Danshen; CA, caffeic acid; PCA, protocatechuic acid; EA, ellagic acid; CT, cryptotanshinone; TI, tanshinone I; and TIIA, tanshinone IIA. The target protein names are detailed in Table S4 (Supplementary Materials).

Inline graphic — Summary of synergistic mechanisms of SD bioactives in the vascular subnetwork: (a) component–target protein (round) or metabolite (triangle)–pathway network (); (b) complete sequence of six major metabolic pathways. The numbers in the box indicate the level of measured metabolites for the placebo (left) and SD (right) consumption group. SD, Sanghuang–Danshen; CA, caffeic acid; PCA, protocatechuic acid; EA, ellagic acid; CT, cryptotanshinone; TI, tanshinone I; and TIIA, tanshinone IIA. The target protein names are detailed in Table S4 (Supplementary Materials).