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. 2018 Dec 28;11(1):17. doi: 10.3390/v11010017

Figure 5.

Figure 5

Disruption in the 5′UTR nt 95–110:NS5B nt 8528–8543 duplex reduced progeny virus titers. Huh-7.5 cells were infected with HCV parental virus (WT) or HCV containing mutations at 5′UTR nt 95–110 and NS5B nt 8528–8543. Plots represent the average number of infectious virus titers as focus-forming units (FFU)/mL or HCV RNA genome copies ± SE in 1 μg of cellular RNA taken at 48 h post-infection. p-values ≤ 0.05 (*) or ≤ 0.01 (**) were determined by the Student’s t-test and represent six independent experiments.