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. 2019 Jan 8;11(1):34. doi: 10.3390/v11010034

Figure 3.

Figure 3

sPLS-DA and VIP score of Cytokine expression profile in Dengue fever vs Severe Dengue Patients. The Sparse Partial Least Squares Discriminant Analysis (sPLS-DA) depicting the cluster between the multiplex cytokine expression profile between the dengue fever (with and without warning signs) vs severe dengue patients (Figure 3a). The red circle represents for the multiplex cytokine expression for dengue fever, while the green color depicted for severe dengue patients (3b). The variable importance in the projection (VIP) score for the multiplex cytokine profile summarizes the contributions of the variables depicted in the model (3b). The expression of cytokines IFN-γ, IL-10, G-CSF, GRO, RANTES, and FGF-2 is higher in severe dengue compared to dengue fever patients.