Effects of ACE2 overexpression in the RVLM on changes in cardiovascular activity (BP, HR, and RSNA) induced by microinjection of atropine into the RVLM in SHRs. Original tracings (A) and maximum changes in BP (B), HR (C), and RSNA (D) in response to microinjections of atropine into the RVLM of SHRs after injection with Lenti-GFP or Lenti-ACE2. Values are mean ± SEM, n = 5/group, *P < 0.05 vs Lenti-GFP.