Table 1.
Mean arterial pressure (MAP) and heart rate (HR) before and after microinjection of A-779 into the PVN.
| Group | Before | After | ||
|---|---|---|---|---|
| MAP (mmHg) | HR (beats/min) | MAP (mmHg) | HR (beats/min) | |
| HS + PVN A-779 | 145 ± 4* | 369 ± 4 | 126 ± 7*† | 365 ± 6 |
| HS + PVN vehicle | 144 ± 3* | 382 ± 4 | 145 ± 5* | 384 ± 6 |
| NS + PVN A-779 | 103 ± 5 | 358 ± 5 | 99 ± 6 | 355 ± 6 |
| NS + PVN vehicle | 100 ± 6 | 349 ± 7 | 99 ± 5 | 344 ± 4 |
NS, normal salt diet; HS, high salt diet; PVN, paraventricular nucleus. All values are presented as mean ± SEM (n = 7); *P < 0.05 versus NS groups; †P < 0.05 after versus before microinjection of A-779 into the PVN.