Table 1.
The association between SLC family 39 genes expression and treatments of GC patients
| Gene | Treatments | Cases | HR (95% CI) | p-value |
|---|---|---|---|---|
| SLC39A1 | Surgery alone | 380 | 0.8 (0.59-1.08) | 0.15 |
| 5-FU based adjuvant | 153 | 1.36 (0.96-1.93) | 0.085* | |
| Other adjuvant | 76 | 1.59 (0.53-4.77) | 0.4008 | |
| SLC39A2 | Surgery alone | 380 | 1.51 (1.1-2.07) | 0.01* |
| 5-FU based adjuvant | 153 | 1.4 (0.98-2) | 0.066 | |
| Other adjuvant | 76 | 0.74 (0.3-1.8) | 0.5 | |
| SLC39A3 | Surgery alone | 380 | 1.4 (1.01-1.92) | 0.041* |
| 5-FU based adjuvant | 34 | 2.41 (0.67-8.61) | 0.16 | |
| Other adjuvant | 76 | 0.4 (0.17-0.98) | 0.037* | |
| SLC39A4 | Surgery alone | 380 | 1.26 (0.91-1.73) | 0.16 |
| 5-FU based adjuvant | 153 | 1.64 (1.14-2.35) | 0.0073* | |
| Other adjuvant | 76 | 0.41 (0.17-1.01) | 0.044* | |
| SLC39A5 | Surgery alone | 380 | 1.41 (1.03-1.94) | 0.032* |
| 5-FU based adjuvant | 34 | 1.44 (0.58-3.61) | 0.43 | |
| Other adjuvant | 76 | 0.35 (0.1-1.2) | 0.082 | |
| SLC39A6 | Surgery alone | 380 | 1.34 (1.01-1.8) | 0.044* |
| 5-FU based adjuvant | 34 | 0.5 (0.18-1.41) | 0.18 | |
| Other adjuvant | 76 | 0.26 (0.06-1.13) | 0.053 | |
| SLC39A7 | Surgery alone | 380 | 0.72 (0.51-1) | 0.052 |
| 5-FU based adjuvant | 153 | 0.68 (0.46-1.02) | 0.062 | |
| Other adjuvant | 76 | 0.34 (0.14-0.81) | 0.011* | |
| SLC39A8 | Surgery alone | 380 | 1.38 (1.03-1.85) | 0.032* |
| 5-FU based adjuvant | 153 | 1.42 (0.93-2.18) | 0.1 | |
| Other adjuvant | 76 | 0.56 (0.2-1.55) | 0.26 | |
| SLC39A9 | Surgery alone | 380 | 0.78 (0.56-1.06) | 0.11 |
| 5-FU based adjuvant | 153 | 1.48 (1.02-2.15) | 0.038* | |
| Other adjuvant | 76 | 2.38 (0.91-6.21) | 0.067 | |
| SLC39A10 | Surgery alone | 380 | 1.2 (0.9-1.6) | 0.21 |
| 5-FU based adjuvant | 34 | 6.83 (2.3-20.31) | 9.6e-05* | |
| Other adjuvant | 76 | 5.23 (1.21-22.54) | 0.013* | |
| SLC39A11 | Surgery alone | 380 | 0.74 (0.55-0.99) | 0.044* |
| 5-FU based adjuvant | 34 | 0.74 (0.3-1.84) | 0.51 | |
| Other adjuvant | 76 | 0.24 (0.09-0.66) | 0.0027* | |
| SLC39A12 | Surgery alone | 380 | 1.24 (0.9-1.7) | 0.18 |
| 5-FU based adjuvant | 34 | 0.42 (0.14-1.28) | 0.12 | |
| Other adjuvant | 76 | 1.79 (0.74-4.29) | 0.19 | |
| SLC39A13 | Surgery alone | 380 | 1.39 (1.04-1.86) | 0.026* |
| 5-FU based adjuvant | 34 | 3.53 (1.26-9.87) | 0.011* | |
| Other adjuvant | 76 | 3.76 (1.53-9.22) | 0.0019* | |
| SLC39A14 | Surgery alone | 380 | 0.6 (0.44-0.82) | 0.0011* |
| 5-FU based adjuvant | 153 | 1.39 (0.98-1.97) | 0.067 | |
| Other adjuvant | 76 | 0.23 (0.1-0.57) | 0.00044* |
The * is mean significant p value.