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. 2019 Jan 31;12(Suppl 1):13. doi: 10.1186/s12920-018-0453-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Functional impact of the AD-associated exon skipping event (exon 23) in NOS1. a Skipping of exon 23. b Normalized expression levels for exon 23 between AD and CN participants. c Structure alignment of the pair of transcript1 retaining exon 23 (green) and transcript 2 with the exon skipping (red)