Table 4.
Association between D-dimer and 28-day outcome
| Non-adjusted | Adjust I | Adjust II | |
|---|---|---|---|
| D-dimer | 1.4 (1.2, 1.7) < 0.001 | 1.4 (1.1, 1.7) 0.010 | 1.4 (1.0, 1.9) 0.030 |
| D-dimer | |||
| < 6.5 mg/L FEU | 1 | 1 | 1 |
| ≥6.5 mg/L FEU | 8.1 (2.4, 27.1) 0.001 | 11.9 (2.3, 63.3) 0.004 | 10.3 (1.3, 81.5) 0.028 |
| delta D-dimera | |||
| ≥0 (stable or decreased) | 1 | 1 | 1 |
| < 0 (elevated) | 6.3 (1.2, 32.3) 0.026 | 9.9 (1.5, 65.0) 0.017 | 27.5 (0.9, 814.9) 0.055 |
Non-adjusted model adjust for: None
Adjust I model adjust for: age; international normalized ratio; leukocyte counts; serum bilirubin and serum creatinine
Adjust II model adjust for: age, red blood cells, hematocrit, albumin, neutrophil percentage, serum total bilirubin, international normalized ratio, C-reactive protein, hepatic encephalopathy, and ascites
adelta D-dimer was analyzed in 51 subjects with repeated D-dimer test at day 4–10 after admission. delta D-dimer = D-dimer (at admission)-D-dimer (at day 4–10)