Fig. 1.

Disease activity parameters in active vs remission/low disease activity (LDA). a Scatter dot plot portraying the percentage of immunoglobulin G subtype 4 (IgG4) from total IgG RNA molecules in the active vs remission/LDA groups in patients with granulomatosis with polyangiitis (GPA). The gray dots within the remission/LDA group represent the three LDA patients. b–e Scatter dot plots showing erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), antineutrophil cytoplasmic antibodies (ANCA), and serum IgG4, respectively, in the active vs remission/LDA groups in GPA (median with IQR). **** p < 0.0001, ** p < 0.01, * p < 0.05, ns = not significant