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. 2019 Jan 31;11:13. doi: 10.1186/s13195-019-0470-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — ¹⁸F-flortaucipir in nfvPPA. a Voxel-wise contrast (pFWE< 0.05) of 11 nfvPPA patients with 53 normal controls with age as covariate. b W-score frequency map showing number of patients with suprathreshold age-adjusted SUVR values (w-score ≥ 1.65) compared to normal controls. Peak voxels suggest eight of 11 subjects have elevated w-score voxels in the same region. c ¹⁸F-flortaucipir SUVR values for each pre-specified region of interest; horizontal bar denotes mean. L, left; NC, normal control; SF, superior frontal. ***p ≤ 0.001, **p ≤ 0.01, *p ≤ 0.05