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Patient 1. A, Clinical presentation characterized by the presence of inflammatory papules, nodules, abscesses, and fistulae in the perineal area as well as the buttocks. B, Psoriasiform eruption on adalimumab located at the lower limbs. C and D, Secukinumab therapy (300 mg at week 0, 1, 2, 3, 4 and then every 4 weeks) achieving partial HS improvement and psoriasiform eruption resolution within the first 8 weeks of treatment.
