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. 2019 Jan 25;10:11. doi: 10.3389/fendo.2019.00011

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Copyright © 2019 Wang, Liu, Liu, Zhu, Tanizaki, Fu, Bao, Shi and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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K-means clustering profile of DETs during tail resorption. A total of 4,555 DETs were grouped into twenty-six clusters based on their developmental regulation patterns. (Note that as there are three possible changes in gene expression between any two stages: up, down and unchanged, there are totally 27 possible clusters among 4 stages. One cluster, i.e., the one with no changes in gene expression among 4 stages, is absent among the DETs.) Each gray line represents one transcript and the average relative expression levels of all transcripts are shown as a blue line. The vertical axis represents the expression level and the horizontal axis shows the four developmental stages. The cluster number is shown as a bold number in the upper left corner and the number in the upper-right corner of each cluster indicates the number of transcripts in the cluster.