Table 5.
GO Terms Associated With Lipid Metabolism-Related Proteins Present in Duodenal Biopsy Specimens 6 Hours After a High-Fat Liquid Meal
| Cholesterol/steroid metabolism | |
| UP_KEYWORDS | Cholesterol biosynthesis |
| GOTERM_BP_DIRECT | Cholesterol biosynthetic process |
| UP_KEYWORDS | Cholesterol metabolism |
| UP_KEYWORDS | Steroid biosynthesis |
| KEGG_PATHWAY | Steroid hormone biosynthesis |
| UP_KEYWORDS | Steroid metabolism |
| UP_KEYWORDS | Sterol biosynthesis |
| GOTERM_MF_DIRECT | Sterol esterase activity |
| UP_KEYWORDS | Sterol metabolism |
| CLD storage/metabolism | |
| GOTERM_CC_DIRECT | Lipid droplet |
| GPTERM_BP_DIRECT | Lipid storage |
| CM trafficking | |
| GOTERM_CC_DIRECT | COPII vesicle coat |
| GOTERM_CC_DIRECT | ER to Golgi transport vesicle membrane |
| GOTERM_MF_DIRECT | SNARE binding |
| GOTERM_CC_DIRECT | SNARE complex |
| GOTERM_BP_DIRECT | Vesicle fusion |
| Eicosanoid metabolism | |
| UP_KEYWORDS | Leukotriene biosynthesis |
| GOTERM_BP_DIRECT | Leukotriene biosynthetic process |
| GOTERM_BP_DIRECT | Leukotriene metabolic process |
| GOTERM_BP_DIRECT | Prostaglandin biosynthetic process |
| FA modification/metabolism/transport | |
| GOTERM_BP_DIRECT | Fatty acid biosynthetic process |
| GOTERM_MF_DIRECT | 3-hydroxyacyl-CoA dehydrogenase activity |
| INTERPRO | 3-hydroxyacyl-CoA dehydrogenase, conserved site |
| INTERPRO | 3-hydroxyacyl-CoA dehydrogenase, C-terminal |
| INTERPRO | 3-hydroxyacyl-CoA dehydrogenase, NAD binding |
| GOTERM_MF_DIRECT | Acyl-CoA dehydrogenase activity |
| INTERPRO | Acyl-CoA dehydrogenase, conserved site |
| INTERPRO | Acyl-CoA dehydrogenase/oxidase |
| INTERPRO | Acyl-CoA dehydrogenase/oxidase C-terminal |
| INTERPRO | Acyl-CoA dehydrogenase/oxidase, N-terminal |
| GOTERM_MF_DIRECT | Acyl-CoA hydrolase activity |
| GOTERM_BP_DIRECT | Acyl-CoA metabolic process |
| INTERPRO | Acyl-CoA oxidase |
| PIR_SUPERFAMILY | Acyl-CoA oxidase |
| INTERPRO | Acyl-CoA oxidase, C-terminal |
| INTERPRO | Acyl-CoA oxidase/dehydrogenase, central domain |
| INTERPRO | AMP binding, conserved site |
| INTERPRO | AMP-dependent synthetase/ligase |
| GOTERM_MF_DIRECT | Decanoate-CoA ligase activity |
| INTERPRO | Domain of unknown function DUF4009 |
| GOTERM_BP_DIRECT | Fatty acid β-oxidation |
| GOTERM_BP_DIRECT | Fatty acid β-oxidation using acyl-CoA dehydrogenase |
| GOTERM_BP_DIRECT | Fatty acid β-oxidation using acyl-CoA oxidase |
| KEGG_PATHWAY | Fatty acid biosynthesis |
| KEGG_PATHWAY | Fatty acid degradation |
| GOTERM_BP_DIRECT | Fatty acid elongation |
| GOTERM_BP_DIRECT | Fatty acid metabolic process |
| KEGG_PATHWAY | Fatty acid metabolism |
| GOTERM_BP_DIRECT | Fatty acid transport |
| GOTERM_MF_DIRECT | Fatty-acyl-CoA binding |
| GOTERM_BP_DIRECT | Fatty-acyl-CoA biosynthetic process |
| GOTERM_BP_DIRECT | Lipid homeostasis |
| GOTERM_BP_DIRECT | Long-chain fatty acid import |
| GOTERM_BP_DIRECT | Long-chain fatty acid metabolic process |
| GOTERM_MF_DIRECT | Long-chain fatty acid-CoA ligase activity |
| GOTERM_BP_DIRECT | Long-chain fatty-acyl-CoA biosynthetic process |
| GOTERM_BP_DIRECT | Long-chain fatty-acyl-CoA metabolic process |
| GOTERM_MF_DIRECT | Very long-chain fatty acid-CoA ligase activity |
| Lipid binding proteins | |
| INTERPRO | Acyl-CoA-binding protein, ACBP |
| INTERPRO | Acyl-CoA-binding protein, ACBP, conserved site |
| INTERPRO | Cytosolic fatty-acid binding |
| UP_SEQ_FEATURE | Domain: ACB |
| INTERPRO | Lipocalin/cytosolic fatty-acid binding protein domain |
| INTERPRO | Lipocalin/cytosolic fatty-acid binding protein domain |
| GOTERM_MF_DIRECT | Retinal binding |
| GOTERM_MF_DIRECT | Retinoic acid binding |
| GOTERM_MF_DIRECT | Retinoid binding |
| GOTERM_MF_DIRECT | Retinol binding |
| UP_KEYWORDS | Retinol binding |
| UP_KEYWORDS | Retinol binding |
| UP_KEYWORDS | Vitamin A |
| Lipoprotein metabolism | |
| INTERPRO | Apolipoprotein A1/A4/E |
| GOTERM_MF_DIRECT | Cholesterol binding |
| GOTERM_BP_DIRECT | Cholesterol efflux |
| GOTERM_BP_DIRECT | Cholesterol homeostasis |
| GOTERM_BP_DIRECT | Cholesterol metabolic process |
| GOTERM_MF_DIRECT | Cholesterol transporter activity |
| GOTERM_CC_DIRECT | Chylomicron |
| UP_KEYWORDS | Chylomicron |
| GOTERM_BP_DIRECT | Chylomicron remnant clearance |
| UP_KEYWORDS | HDL |
| GOTERM_CC_DIRECT | High-density lipoprotein particle |
| GOTERM_BP_DIRECT | High-density lipoprotein particle assembly |
| GOTERM_BP_DIRECT | High-density lipoprotein particle clearance |
| GOTERM_MF_DIRECT | High-density lipoprotein particle receptor binding |
| GOTERM_BP_DIRECT | High-density lipoprotein particle remodeling |
| GOTERM_CC_DIRECT | Intermediate-density lipoprotein particle |
| UP_KEYWORDS | LDL |
| SMART | LDLa |
| GOTERM_MF_DIRECT | Lipase inhibitor activity |
| UP_KEYWORDS | Lipid transport |
| GOTERM_BP_DIRECT | Lipid transport |
| GOTERM_MF_DIRECT | Lipid transporter activity |
| GOTERM_BP_DIRECT | Lipoprotein biosynthetic process |
| GOTERM_BP_DIRECT | Lipoprotein metabolic process |
| INTERPRO | LDL-receptor class A repeat |
| INTERPRO | LDL-receptor class A, conserved site |
| GOTERM_CC_DIRECT | LDL particle |
| GOTERM_BP_DIRECT | LDL particle remodeling |
| GOTERM_BP_DIRECT | Negative regulation of cholesterol transport |
| GOTERM_BP_DIRECT | Negative regulation of lipid catabolic process |
| GOTERM_BP_DIRECT | Negative regulation of lipid metabolic process |
| GOTERM_BP_DIRECT | Negative regulation of receptor-mediated endocytosis |
| GOTERM_BP_DIRECT | Negative regulation of VLDL particle clearance |
| GOTERM_BP_DIRECT | Negative regulation of VLDL particle remodeling |
| GOTERM_BP_DIRECT | Neuron projection regeneration |
| GOTERM_MF_DIRECT | Phosphatidylcholine binding |
| GOTERM_MF_DIRECT | Phosphatidylcholine-sterol O-acyltransferase activator activity |
| GOTERM_BP_DIRECT | Phospholipid efflux |
| GOTERM_BP_DIRECT | Positive regulation of cholesterol esterification |
| GOTERM_BP_DIRECT | Positive regulation of fatty acid biosynthetic process |
| GOTERM_BP_DIRECT | Positive regulation of lipoprotein lipase activity |
| GOTERM_BP_DIRECT | Positive regulation of triglyceride catabolic process |
| GOTERM_BP_DIRECT | Regulation of Cdc42 protein signal transduction |
| GOTERM_BP_DIRECT | Regulation of intestinal cholesterol absorption |
| GOTERM_BP_DIRECT | Reverse cholesterol transport |
| GOTERM_CC_DIRECT | Spherical HDL particle |
| GOTERM_BP_DIRECT | Triglyceride homeostasis |
| GOTERM_CC_DIRECT | VLDL particle |
| GOTERM_BP_DIRECT | VLDL particle remodeling |
| UP_KEYWORDS | VLDL |
| TAG and PL synthesis/metabolism | |
| GOTERM_MF_DIRECT | 1-acylglycerol-3-phosphate O-acyltransferase activity |
| GOTERM_BP_DIRECT | Acylglycerol catabolic process |
| GOTERM_MF_DIRECT | Acylglycerol lipase activity |
| GOTERM_BP_DIRECT | CDP-diacylglycerol biosynthetic process |
| GOTERM_BP_DIRECT | Ether lipid biosynthetic process |
| GOTERM_BP_DIRECT | Glycerolipid metabolic process |
| GOTERM_BP_DIRECT | Glycerophospholipid biosynthetic process |
| GOTERM_BP_DIRECT | Glycerophospholipid catabolic process |
| KEGG_PATHWAY | Glycerophospholipid metabolism |
| GOTERM_BP_DIRECT | GPI anchor biosynthetic process |
| GOTERM_MF_DIRECT | Lysophospholipase activity |
| GOTERM_BP_DIRECT | Phosphatidic acid biosynthetic process |
| UP_KEYWORDS | Phospholipid biosynthesis |
| GOTERM_BP_DIRECT | Phospholipid biosynthetic process |
| GOTERM_BP_DIRECT | Phospholipid catabolic process |
| GOTERM_BP_DIRECT | Phospholipid metabolic process |
| UP_KEYWORDS | Phospholipid metabolism |
| GOTERM_BP_DIRECT | Phospholipid transport |
| INTERPRO | Phospholipid/glycerol acyltransferase |
| SMART | PlsC |
| UP_SEQ_FEATURE | Short sequence motif: HXXXXD motif |
| GOTERM_BP_DIRECT | Triglyceride biosynthetic process |
| GOTERM_MF_DIRECT | Triglyceride lipase activity |
ABCP, Acyl-CoA-binding protein; ACB, acyl-CoA-binding; AMP, Adenosine monophosphate; CDP, Cytidine Diphosphate; COPII, cytoplasmic coat protein complex II; GPI, glycosylphosphatidylinositol; HDL, high-density lipoprotein; LDL, low-density lipoprotein; LDLa, low-density lipoprotein receptor domain class A; NAD, Nicotinamide adenine dinucleotide.