Table 3.
Comparison of IC50 cytotoxicity values of 1-Ga, Ga(ACtpfc) and Ga(3-ctpfc) in human cancer cell lines. Reproduced from ref. 114. Copyright 2016 National Academy of Sciences.
Cell line | DU145 | SK-MEL-28 | MDA-MB-231 | OVCAR-3 | |
---|---|---|---|---|---|
Tumor type | prostate | Melanoma | breast | ovarian | |
IC50 (µM) | 1-Ga | 158.9 | 131.4 | 129.2 | 274.2 |
Ga(ACtpfc) | 17.6 | 14.4 | 13.7 | 12.7 | |
Ga(3-ctpfc) | 12.9 | 4.8 | 15.3 | 11.1 |