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CTS suppresses STAT3 activation.
Notes: (A) Basic expression levels of STAT3 in CAES17, EC109, SW1990 and BXPC3 cell lines were detected by Western blot. (B, C) JAK2, p-JAK2, STAT3 and p-STAT3 (Tyr705) were detected after treatment with indicated concentrations of CTS for 24 hours or different times in both EC109 and CAES17 cell lines by Western blotting assay.
Abbreviations: CTS, cryptotanshinone; JAK2, janus kinase-2; p, phosphorylated.
