Lower frequency of CD71+ erythroid cells in IBD patients during pregnancy. [A] Representative dot plots showing frequency of CD71+ erythroid cells in the peripheral blood of ulcerative colitis [UC], Crohn’s disease [CD]. and healthy controls [HC] in the third trimester [T3]. [B] Percentages of CD71+ erythroid cells in the peripheral blood of pregnant women [T3], either those with UC or CD, or HCs. [C] Percentages of Tregs at T3 in inflammatory bowel disease [IBD] versus HCs. [D] Correlation of % Tregs with % CD71+ cells in IBD patents. [E] Representative dot plots showing how Tregs are defined. [F] Representative dot plots showing frequency of CD71+ erythroid cells in placental tissues of UC, CD, and HC. [G] Percentages of CD71+ erythroid cells in placental tissues of UC, CD or HCs. [H] Correlation of activated cells [CD71+ cells lymphocytes] with frequency of CD71+ erythroid cells in placenta. [I] Percentages of caesarean section [C-section] in HC versus IBD pregnancies in the cohort. [J] Percentages of preterm deliveries by HC versus IBD mothers in the cohort. [K] Detected levels of serum erythropoietin [EPO] by ELISA at T3 in IBD versus HCs.