Table 1.

ME/CFS overlap syndromes.

These co-morbidities have been associated with ME/CFS or occur more commonly in Persons with Chronic Fatigue Syndrome (PWCs) than the general population: Fibromyalgia Myofascial Pain Syndrome Irritable Bowel Syndrome Overactive bladder or Interstitial Cystitis Postural Orthostatic Tachycardia Syndrome Neurally Mediated Hypotension Mast Cell Activation Syndrome Hypogonadism and premature menopause Sleep disorders (sleep apnea, myoclonus / PLMS, non-restorative sleep) Restless Leg Syndrome / Periodic Leg Movement syndrome Multiple Chemical Sensitivities Hypersensitivities to light, sound, smell, touch, chemicals or odors Sacroiliac joint tenderness Hypoglycemia Mitral valve prolapse Premenstrual Syndrome or Premenstural Dysphoric Disorder Allergies Vasomotor (autonomic or non-allergic) rhinitis B12 deficiency Gut motility disorder with dysphagia, early satiety, nausea, and/or constipation Celiac- or sprue-like disorders with sensitivity to wheat, grains, or gluten Autonomic dysfunction with low blood pressure, orthostatic symptoms Sicca complex or Sjogren's syndrome Bronchostriction (reactive airways or asthma) Macrocytosis (large red cells, causes low sedimentation rate) Abdomino-pelvic pain Vulvodynia or vulvar vestibulitis Joint hyperlaxity with or without hyperelasticity (Ehlers-Danlos Stigmata) Milk protein intolerance Costochondritis Endometriosis Metabolic Syndrome Temperomandibular Dysfunction