Table 4.

The predictive power of CTA-based truncal-type occlusions for angiography-revealed significant fixed focal stenosis, and comparison with initial reports and other imaging modalities.

References	Population	Univariate P	Multivariate P	Sensitivity	Specificity	PPV	NPV	Accuracy	+LR	–LR
Truncal-type occlusions in prediction of angiography-revealed significant fixed focal stenosis
Current study	ICA + MCA + VBA	<0.001	<0.001*	50.5%	87.4%	50.5%	87.4%	80.0%	4.02	0.57
	Intracranial ICA	0.261	0.358*	26.3%	83.9%	15.2%	91.3%	78.2%	1.64	0.88
	MCA M1	<0.001	<0.001*	41.9%	92.3%	63.4%	83.2%	80.1%	5.42	0.63
	VBA	<0.001	0.004*	95.5%	79.0%	72.4%	96.8%	85.0%	4.54	0.06
CTA truncal-type occlusions in prediction of SR failure
Baek et al. (26)	ICA + MCA + VBA			48.2%	90.8%	60.5%	85.6%	81.1%	5.21	0.57
Truncal-type occlusions after STENT deployment in prediction of SR failure
Baek et al. (25)	ICA+MCA+VBA			30.5%	97.6%	–	–	–	12.6	0.71
Other imaging predictors
Negative susceptibility vessel sign in prediction of ICAS-related occlusion
Kim et al. (23)	MCA	<0.001		100.0%	67.1%	42.9%	100.0%	73.6%	3.04	0.00
Suh et al. (24)	ICA+MCA	0.239		28.6%	75.0%	–	–	–	1.14	0.95
Negative multi-segment clot sign in prediction of large artery atherosclerosis
Chen et al. (32)	ICA+MCA	<0.001		90.7%	52.7%	42.9%	93.5%	63.4%	1.92	0.18

^*Multivariate analysis was performed with age, gender, smoking, and atrial fibrillation as covariates. Predictive values from these articles have been calculated through statistical analysis of data presented in the literature. CTA, computed tomographic angiography; PPV, positive predictive value; NPV, negative predictive value; +LR, positive likelihood ratio; –LR, negative likelihood ratio; ICA, internal carotid artery; MCA, middle cerebral artery; VBA, vertebrobasilar artery; SR, stent retriever; ICAS, intracranial atherosclerotic stenosis.