Table 1.

Baseline clinical, laboratory and genetic characteristics of enrolled patients.

Characteristics
Female, n(%)	18 (40%)
ISS Stage, n(%)
I	22 (49%)
II	22 (49%)
III	1 (2%)
Median age (range) years	60 (40–88)
Isotype, n(%)[median, range]
IgG kappa g/dL	23 (51%)[3.1,0–7.1]
IgG lambda g/dL	7 (15.5%)[2.8, 0–7.6]
IgA kappa g/dL	6 (13.3%)[1.35,0–1.8)
IgA lambda g/dL	4 (8.88%)[1.6,1.4–2.8]
Kappa light chain mg/dL	4 (8.88%)[243,39.5–1620]
Lambda light chain[actual value] mg/dL	1 (2%)[51.6]
Clinical end-organ damage, n(%)
Lytic lesions	37 (82%)
Anemia	12 (27%)
Hypercalcemia	3 (7%)
Renal insufficiency	0
Cytogenetics*, n(%)
Normal	33 (78%)
Hyperdiploidy	5 (11%)
t(11;14)	1 (2%)
del(11)	2 (4.5%)
del(17p)	1 (2%)
FISH#, n(%)
Normal	9 (20%)
Hyperdiploidy	17 (38%)
t(11,14)	4 (9%)
del(13q)	11 (24.5%)
del(17p)	5 (11%)

ISS: international staging system; M-spike: monoclonal spike; FISH: fluorescence in-situ hybridization.

^*missing 1,

^#missing 6,

^*#none of the patients had the following genetic abnormalities: t(4;14), t(14;16),t(14;20).