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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Pediatr Allergy Immunol. 2018 Nov 20;30(1):117–122. doi: 10.1111/pai.12995

Table 3. Associations between maternal 25(OH)D levels and allergic outcomes (odds ratio and 95% confidence intervals).


25(OH)D sufficiency
(≥ 75nmol/l)
OR (95% CI)*
25(OH)D insufficiency
(≥50 nmol/l and <75 nmol/l)
OR (95% CI)*
25(OH)D deficiency
(<50 nmol/l)
OR (95% CI)*
Outcomes by month 18

Allergen sensitization Ref 0.7 (0.3-1.3) 1.2 (0.5-2.6)
Eczema Ref 0.9 (0.5-1.6) 1.4 (0.7-2.9)
Rhinitis Ref 0.9 (0.5-1.6) 0.9 (0.4-2.1)
Wheeze and use nebulizer Ref 0.7 (0.3-1.5) 0.7 (0.3-1.8)

Outcomes by month 36

Allergen sensitization Ref 0.6 (0.3-1.1) 1.2 (0.6-2.5)
Eczema Ref 1.0 (0.6-1.8) 1.5 (0.8-3.1)
Rhinitis Ref 1.1 (0.7-2.0) 1.3 (0.6-2.8)
Wheeze and use nebulizer Ref 0.6 (0.3-1.2) 0.5 (0.2-1.3)

Outcomes by month 60

Allergen sensitization Ref 0.7 (0.4-1.1) 0.9 (0.4-1.8)
Eczema Ref 1.1 (0.6-1.8) 1.6 (0.8-3.2)
Rhinitis Ref 1.2 (0.7-2.1) 1.3 (0.6-2.7)
Wheeze and use nebulizer Ref 1.0 (0.6-1.7) 0.9 (0.4-1.9)

*

Adjusted for sex, ethnicity, maternal education levels, maternal age, maternal BMI during pregnancy, family history of allergy, total energy intake during pregnancy and vitamin D supplementation.