Table 3. Associations between maternal 25(OH)D levels and allergic outcomes (odds ratio and 95% confidence intervals).
25(OH)D sufficiency (≥ 75nmol/l) OR (95% CI)* |
25(OH)D insufficiency (≥50 nmol/l and <75 nmol/l) OR (95% CI)* |
25(OH)D deficiency (<50 nmol/l) OR (95% CI)* |
|
---|---|---|---|
Outcomes by month 18 | |||
Allergen sensitization | Ref | 0.7 (0.3-1.3) | 1.2 (0.5-2.6) |
Eczema | Ref | 0.9 (0.5-1.6) | 1.4 (0.7-2.9) |
Rhinitis | Ref | 0.9 (0.5-1.6) | 0.9 (0.4-2.1) |
Wheeze and use nebulizer | Ref | 0.7 (0.3-1.5) | 0.7 (0.3-1.8) |
Outcomes by month 36 | |||
Allergen sensitization | Ref | 0.6 (0.3-1.1) | 1.2 (0.6-2.5) |
Eczema | Ref | 1.0 (0.6-1.8) | 1.5 (0.8-3.1) |
Rhinitis | Ref | 1.1 (0.7-2.0) | 1.3 (0.6-2.8) |
Wheeze and use nebulizer | Ref | 0.6 (0.3-1.2) | 0.5 (0.2-1.3) |
Outcomes by month 60 | |||
Allergen sensitization | Ref | 0.7 (0.4-1.1) | 0.9 (0.4-1.8) |
Eczema | Ref | 1.1 (0.6-1.8) | 1.6 (0.8-3.2) |
Rhinitis | Ref | 1.2 (0.7-2.1) | 1.3 (0.6-2.7) |
Wheeze and use nebulizer | Ref | 1.0 (0.6-1.7) | 0.9 (0.4-1.9) |
Adjusted for sex, ethnicity, maternal education levels, maternal age, maternal BMI during pregnancy, family history of allergy, total energy intake during pregnancy and vitamin D supplementation.