Effect of pao pereira extract (10, 20, and 50 mg/kg) on LNCaP tumor xenograft growth in immunodeficient mice A, Box plot of baseline tumor volumes for control and pao pereira treatment groups. A statistically significant difference was observed across all dose groups (p = .025, Kruskal-Wallis test). B, Overall tumor volume in mouse xenografts was reduced in 10 mg/kg and 20 mg/kg pao pereira–treated mice. *p = .005, ANOVA (median log tumor volume).