High-resolution histogram-equalized images (left) and normalized class
activation maps (CAMs) (224 × 224 resolution) (right) show
(a) true-positive (decreased right lung volume;
convolutional neural network [CNN] score 0.99), (b)
false-positive (necklace; CNN score 0.57), (c) false-negative
(borderline cardiomegaly; CNN score 0.48), and (d)
true-negative (humerus fracture; CNN score 0.41) findings of thoracic
disease. Red indicates areas of relatively high contribution to an abnormal
score, while blue areas indicate the opposite. Because color information is
normalized within each image, comparison of values across CAMs is not
appropriate.