Table 3. Univariate proportional hazard regression of patient survival for tested variables.
Variable | Factora | N | Relative risk | 95% confidence interval | P | Overall model significance |
---|---|---|---|---|---|---|
Gender | F | 16 | 1 | P = 0.207 | ||
M | 65 | 1.5 | 0.7 to 2.9 | 0.229 | ||
Age | continuous | 81 | 1 | 0.9 to 1.1 | 0.063 | P = 0.062 |
Age | <45 | 6 | P = 0.127 | |||
45–64 | 51 | 2.8 | 0.9 to 9.2 | 0.081 | ||
65+ | 24 | 2.6 | 0.8 to 8.9 | 0.126 | ||
T | 1–2 | 34 | 1 | P = 0.038 | ||
3–4 | 29 | 1.9 | 1.1 to 3.5 | 0.017 | ||
Unknown | 18 | 1.8 | 0.9 to 3.4 | 0.079 | ||
N | 0–1 | 30 | 1 | P = 0.006 | ||
2–3 | 33 | 2.4 | 1.4 to 4.3 | 0.003 | ||
Unknown | 18 | 2.1 | 1.1 to 3.9 | 0.037 | ||
Stage 7th | I-II | 17 | 1 | P = 0.009 | ||
III-IV | 50 | 2.6 | 1.3 to 5.2 | 0.006 | ||
Unknown | 14 | 2.6 | 1.1 to 6.1 | 0.031 | ||
Stage 8th | I-II | 26 | 1 | P = 0.001 | ||
III-IV | 41 | 2.9 | 1.6 to 5.4 | 0.001 | ||
Unknown | 14 | 2.4 | 1.1 to 5.1 | 0.029 | ||
Grade | 1 | 19 | 1 | P = 0.876 | ||
2 | 29 | 1.1 | 0.6 to 2.3 | 0.619 | ||
3 | 31 | 1.1 | 0.6 to 2.2 | 0.711 | ||
Unknown | 2 | 2.4 | 0.5 to 10.7 | 0.246 | ||
HPV overall | no HPV | 49 | 1 | P = 0.893 | ||
inactive HPV | 11 | 0.9 | 0.4 to 1.8 | 0.763 | ||
active HPV | 21 | 1.1 | 0.6 to 1.9 | 0.776 | ||
HPV DNA | no HPV | 49 | 1 | P = 0.964 | ||
HPV DNA+ | 32 | 1.0 | 0.6 to 1.7 | 0.965 | ||
HPV RNA | no HPV | 60 | 1 | P = 0.714 | ||
HPV RNA+ | 21 | 1.1 | 0.6 to 1.9 | 0.712 | ||
p16 | p16 negative | 36 | 1 | P = 0.569 | ||
p16 + | 22 | 1.2 | 0.7 to 2.0 | 0.603 | ||
Unknown | 23 | 0.8 | 0.4 to 1.5 | 0.510 | ||
Alcohol | No alcohol | 11 | 1 | P = 0.075 | ||
Occasional use | 18 | 2.3 | 0.8 to 6.4 | 0.103 | ||
Heavy use | 8 | 4.0 | 1.3 to 12.3 | 0.015 | ||
Unknown | 44 | 2.5 | 0.9 to 6.3 | 0.059 | ||
Smoking | No smoking | 8 | 1 | P = 0.279 | ||
Former | 9 | 2.7 | 0.7 to 10.3 | 0.138 | ||
Current | 20 | 2.7 | 0.8 to 9.1 | 0.115 | ||
Unknown | 44 | 2.7 | 0.8 to 8.7 | 0.099 |
aFactors reaching statistical significance are highlighted by bold font