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. 2019 Feb 1;14(2):e0211712. doi: 10.1371/journal.pone.0211712

Table 2. Microbiological results of middle ear fluid (MEF).

Total
n = 470
<3 years n = 331 (70.4%) ≥3 years
n = 139 (29.6%)
p value
Absence of otopathogen 251 (53.4) 156 (47.1) 95 (68.3) <0.001
At least ≥1 otopathogen 219 (46.6) 175 (52.9) 44 (31.7)
Total NTHi 106 (48.4) 93 (53.1) 13 (29.5) 0.005
Total GAS 76 (34.7) 53 (30.3) 23 (52.3) 0.006
Total Sp 61 (27.9) 50 (28.6) 11 (25) 0.6
NTHi alone 77 (35.2) 69 (39.4) 8 (18.2) 0.008
GAS alone 63 (28.8) 41 (23.4) 22 (50) 0.001
Sp alone 37 (16.9) 30 (17.1) 7 (15.9) 0.8
Mc alone 5 (2.3) 4 (2.3) 1 (2.3) 1
Mixtures of otopathogens 37 (16.9) 31 (17.7) 6 (13.6) 0.4
 NTHi+Sp 18 (8.2) 16 (9.1) 2 (4.6) 0.5
 NTHi+ GAS 6 (2.7) 5 (2.9) 1 (2.3) 1
 NTHi+Sp+Mc 3 (1.4) 2 (1.1) 1 (2.3) 0.5
 NTHi+Mc 2 (0.9) 1 (0.6) 1 (2.3) 0.4
 Mc+GAS 5 (2.3) 5 (2.3) 0
 Sp+GAS 2 (0.9) 2 (1.1) 0
 Sp+Mc 1 (0.5) 0 1 (2.3)

Data are n (%). NTHi, non-typable Haemophilus influenzae; GAS, group A streptococcus; Sp, Streptococcus pneumoniae; Mc, Moraxella catharalis