Table 1. AUD mutant replication phenotypes in different cell types.
CHIKV-D-luc SGR | Human | Rodent | Mosquito | ||||
---|---|---|---|---|---|---|---|
Huh7 | Huh7.5 | RD | C2C12 | BHK | U4.4 | C6/36 | |
Wildtype | |||||||
M219A | |||||||
E225A | |||||||
R243A/K245A | |||||||
P247A/V248A | |||||||
V260A/P261A | |||||||
C262A/C264A |
Key: Wildtype replication, impaired replication, no replication. reversion